PhD Defense of Nathan MARTIN
Soutenance de thèseDear All,
It is my pleasure to invite you to the defense of my PhD thesis entitled :
« New methodological developments in photochemistry and photocatalysis applied to the synthesis of functionalized isoindolinones »
The defense will take place on Tuesday, the 17th of December, at 2 pm in the 2A02 amphitheater – IUT A, Villeneuve d’Ascq.
The jury of my defense is composed of:
| Pr. Vincent Dalla | Reporter | URCOM, |
| Dr. Jean-François Brière | Reporter | INSA Rouen |
| Dr. Yann Bernhard | Examiner | L2CM, University of Lorraine |
| Pr. Lydie Pélinski | Examiner | UCCS, University of Lille |
| Dr. Till Bousquet | Thesis supervisor | UCCS, University of Lille |
| Pr. Eric Deniau | Thesis director | UCCS, University of Lille |
Key words
| Photochemistry, photocatalysis, isoindolinone, enamide, diazonium salt, alkoxyarylation, carbamoylation, hydrogen atom transfer, single electron transfer. |
Summary
| For decades, photochemistry has been exploited as an eco-friendly alternative to traditional chemical synthesis. More recently, the rise of photocatalysis, particularly using visible light, has generated growing interest by enabling new reactions. In parallel, isoindolinones, structures present in numerous molecules of interest, especially pharmaceuticals, have also been the subject of extensive studies for many years. Based on the laboratory's expertise in both fields, this manuscript describes the development of new photochemical and photocatalytic methodologies for the functionalization of a platform molecule, 3-methyleneisoindolinone. Thus, starting from this molecule, a photo-induced alkoxyarylation reaction in the presence of aryldiazonium salts, a carbamoylation by photoredox catalysis using Hantzsch ester derivatives, and a photocatalyzed transformation based on a hydrogen atom transfer process are successively detailed. |
After the defense, a get-together party will follow.
I hope to see you there.
Kind regards,
Nathan Martin